Computational prediction of Ds transposon insertion sites in plants using DNA structural features
نویسندگان
چکیده
..................................................................................................................... iii CHAPTER 1 GENERAL INTRODUCTION ................................................................ 1 BIOLOGY OF AC/DS TRANSPOSON .......................................................................................... 1 DNA STRUCTURAL PROPERTIES ............................................................................................. 1 THESIS ORGANIZATION ............................................................................................................ 2 REFERENCES................................................................................................................................ 3 CHAPTER 2. DNAFVP: A PACKAGE FOR DNA FEATURE CALCULATION, VISUALIZATION AND VECTOR PREPARATION ................................................... 5 ABSTRACT .................................................................................................................................... 5 INTRODUCTION .......................................................................................................................... 6 IMPLEMENTATION ...................................................................................................................... 7 DISCUSSION ............................................................................................................................... 15 ACKNOWLEDGEMENTS .......................................................................................................... 15 REFERENCES.............................................................................................................................. 15 FIGURES ...................................................................................................................................... 18 SUPPLEMENTARY INFORMATION ......................................................................................... 20 CHAPTER 3. COMPUTATIONAL PREDICTION OF DS TRANSPOSON INSERTION SITES IN PLANTS USING DNA STRUCTURAL FEATURES ........ 48 ABSTRACT .................................................................................................................................. 48 INTRODUCTION ........................................................................................................................ 49 METHODS ................................................................................................................................... 50 RESULTS AND DISCUSSION .................................................................................................... 54 ACKNOWLEDGEMENTS .......................................................................................................... 60 REFERENCES.............................................................................................................................. 60 TABLES ........................................................................................................................................ 62 FIGURES ...................................................................................................................................... 66 SUPPLEMENTARY INFOMATION ........................................................................................... 68 CHAPTER 4 GENERAL CONCLUSION ................................................................... 79 REFERENCES.............................................................................................................................. 80 ACKNOWLEDGEMENTS ........................................................................................... 83
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